Pickett CB, Lu AY: Glutathione S-transferases: gene structure, regulation, and biological function
The true star among MCTs is caprylic acid (C8) , with 8 carbon atoms according to research published in Ageing Research Reviews, its ketogenic potency is three times greater than capric acid and six times greater than lauric acid [3]
Considering again that the myogenic stem cell activator HGF is found in an ECM-bound state 19,20,21,22,26 and undergoes nitration of tyrosine residues (Y198 and Y250) with aging 32,32,62 and muscle disuse (Kuwakdo et al., 2025), the present in vivo experiments provide a robust platform showing the potential for LASSS that could efficiently reduce or delay the nitration-dysfunction of ECM-bound HGF under peroxynitrite-generating conditions
The increase of local IGF-1 binding protein prevents IGF-1 from freely exerting its biological effects [55]