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Additionally, individuals with diabetes are at a higher risk of experiencing adverse events like pancreatitis, bowel obstruction, diabetic retinopathy, and gallbladder, liver, and bile duct issues, particularly if these conditions are preexisting.38,46 Hypoglycemia is also a risk, particularly when titrating up, and especially if the individual is also taking another medication that may lower blood sugar like insulin, metformin, or sulfonylureas

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Side effects include high blood pressure, cardiovascular effects, insomnia, restlessness, headache, and gastrointestinal issues