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A crossover study in Iranian NS workers demonstrated that night work significantly elevated pro-inflammatory markers, including IL-6, CRP, white blood cells, neutrophils, lymphocytes, and platelets, compared to DS workers, supporting a link between circadian disruption and triggering of systemic inflammation 145

Alcohol impairs fat metabolism, disrupts sleep quality, adds empty calories, and can stress the liver

Mitochondrial content and function in skeletal muscle are regulated by GLP-1.389 The interaction between GLP-1 and its receptor GLP-1R initiates the AMPK signaling cascade within skeletal muscle tissue