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Hold the syringe like a pencil or dart, with your dominant hand

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Four compounds, 55 58 , showed IC 50 values in the range of 26.30 to 55.00 nM, with 55 being the most active in the study, with the 4Cl substituent, and relatively comparable to the positive control, febuxostat, with an IC 50 of 6.91 nM (Figure 17)