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He is a prolific researcher who has published seminal papers about the disease and has for years helped write and update the clinical guidelines for Wilson disease from the American Association for the Study of Liver Diseases (AASLD), in addition to those for the European Association for Liver Disease (EALD)

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To investigate whether albumin could be engineered to evade L585 cleavage and the resulting reduction in FcRn binding, we constructed a panel of 18 full-length 585-engineered human albumin variants, in which the C-terminal leucine residue was substituted with each of the other naturally occurring amino acids, except for cysteine (Fig