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For men with idiopathic (unexplained) infertility, CoQ10 supplementation is associated with statistically significant improvements in sperm concentration, volume, and motility, along with higher clinical pregnancy odds compared to placebo

However, the subsequent ileal inflammation was not reduced

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This threshold is supported by volunteer studies using semaglutide, where residual solids were detected on ultrasound despite 8 h fasting [7], and by matched-pair data showing a five-fold rise in endoscopic residue among GLP-1RA users 7