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Efficacy and safety of semaglutide versus placebo as add-on to basal insulin in insulin-treated patients with type 2 diabetes (SUSTAIN 5)

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Activation of POMC neurons via 5-HT 2C receptors, in the NTS decreases feeding and mediates acute reduced food intake in response to the selective 5-HT 2C receptor agonists, like lorcaserin [96]