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Although the underlying mechanisms responsible for this neuroprotective effect require further investigation, in this study we successfully demonstrate that pathways of ferroptosis and development of A pathology seem to be closely intertwined

The ROS scavenging property of Sp was also replicated in the Drosophila models knocked-down for essential antioxidant enzymes catalase and glutathione peroxidase, where neuronal cells of 15 days AEL flies genetically expressing a redox biosensor, roGFP showed reduced fluorescence under Sp treatment (Fig

In Using Mathematics to Understand Biological Complexity , 135178 (Springer, 2020)