Low-dose lithium , promoted for brain aging after a 2025 Harvard study showed brain lithium is depleted early in Alzheimers and that lithium orotate reversed pathology in mice, has only mixed human trial evidence and works by dampening neuronal firing, so I do not recommend it for a healthy brain
If its painful, spreading, interfering with sleep, or getting worse after a dose increase, its worth asking whether staying at your current dose, lowering the dose, or pausing treatment makes sense
Taken together, the role of inflammation in AILI remains under considerable debate, and this makes it controversial to be as a therapeutic target (Fig
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