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Transforming growth factor (TGF)- family members are potent regulatory cytokines that influence multiple cell types and mediate both proinflammatory and anti-inflammatory responses (Schon and Weiskirchen, 2014)

Lyophilized powders are best stored in the refrigerator or freezer, while all reconstituted solutions are fragile and must be kept refrigerated and used within about 30 days

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Higher levels of pro-inflammatory cytokines, including IL-1, IL-2, IL-4, IL-6, IL-7, IL-10, IL-13, IL-17, M-CSF, G-CSF, GM-CSF, and IP-10 have been reported in severe COVID-19 patients (Rodrigues et al., 2021