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Thus, DSIP helps to prevent excitotoxicity, which may underlie its neuroprotective action in cerebral ischemia[1]

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The highest volume of distribution was observed for diosgenin (2.5 ml/kg) followed by charantin (1.4 ml/kg) and least was observed for hydroxychalcone (0.27 ml/kg), indicating high protein binding of hydroxychalcone and ultimately low t 1/2 and lower clearance of drug from the body