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Demonstrating peripheral effects by suppressing T-cell-mediated inflammation via GLP-1 receptor activation in intestinal lymphocytes, and central effects by mediating Toll-like receptor (TLR)-induced anti-inflammatory responses through GLP-1 receptor signaling in the brain [39]

Physical exercise is known for its widespread effects on human physiology, and its impact has been extensively studied, both acutely and over the long term (reviewed in Kelly et al., 2020)

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