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Purdue scientist Bruce Hamaker is studying how food-derived supplements could trigger the bodys own appetite regulation hormones Drugs like Ozempic and Mounjaro have made regular headlines in recent years for their ability to facilitate weight loss often dramatic weight loss

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Although many people are impressed with the effects of Ozempic, the safety of the medicine is not fully understood

J Biol Chem 284:90599065 Han L, Hiratake J, Kamiyama A, Sakata K (2007) Design, synthesis, and evaluation of gamma-phosphono diester analogues of glutamate as highly potent inhibitors and active site probes of gamma-glutamyl transpeptidase