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Anti-Inflammatory Effects and Metabolic Health Improvement Obesity and type 2 diabetes create a chronic inflammatory state characterized by elevated C-reactive protein, TNF-alpha, and IL-6cytokines linked to joint pain, autoimmune flares, and accelerated aging

This concern was related to the action of DPP-4 to cleave a number of bioactive peptides with alanine or proline as the second amino acid from the N-terminal end apart from GLP-1 and GIP, such as neuropeptide Y, gastrin-releasing peptide, substance P, and various chemokines (25, 26)

Clinical Uses and Benefits The approval of Ozempic for the treatment of type 2 diabetes has been a game-changer in the landscape of diabetes management