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Without adequate glutathione, this detoxification pathway becomes impaired, leading to toxic accumulation and increased oxidative stress as the body struggles to process and eliminate harmful substances

This suggests that the residual inhibition produced by DA in the 2A -adrenergic receptor KO background unmasks the relative contributions of the inhibitory G i -coupled -cell DA D 2 -like receptors that remain expressed

Neurobiol Dis 2010;40:23844

Physicochemical selectivity of the BBB microenvironment governing passive diffusion-matching with a porcine brain lipid extract artificial membrane permeability model