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34 Risk factors for the development of hyperammonaemia whilst undergoing therapy with VPA include the concomitant use of other antiepileptic drugs, concomitant use of mood stabilizers, genetic variability, poor nutritional status, inborn errors in carnitine metabolism and errors in metabolism of urea, and the use of certain HIV medications

It protects cells from oxidative damage by neutralizing free radicals and other reactive oxygen species (ROS)

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Finally, the purity of the fractions was confirmed by Western blot analysis using cytoplasmic marker protein GAPDH and nuclear marker protein Histone H3(HH3)