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Repigmentation and new growth of hairs after anti-interleukin-17 therapy with secukinumab for psoriasis

The authorization was based on the outcome of the SOUL clinical trial

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TPP functions as a cofactor for several critical enzymes across three metabolic pathways: transketolase (TK) in the pentose phosphate pathway, pyruvate dehydrogenase (PDH) in glycolysis, and alpha-ketoglutarate dehydrogenase (AKD) in the Krebs cycle (33, 34)