Dehydration may place strain on your kidneys, and reduced kidney function increases metformin levels in your blood, which in turn raises the risk of lactic acidosis
When prescribing oral semaglutide, patients should be advised to swallow the tablets whole with water (120 mL) at least 30 min prior to the first ingestion of food, beverage, or any other oral medications of the day [24]
Beyond weight loss, the semaglutide and cagrilintide mix produces full gains in body health including dramatic glycemic control gains, blood pressure reductions, improved lipid profiles, reduced swelling, and enhanced quality of life
Muriach M, Flores-Bellver M, Romero FJ et al (2014) Diabetes and the brain: oxidative stress, inflammation, and autophagy