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The tyrosine kinase Src was also shown to phosphorylate MOR at Y336, located in the NPXXY motif, after sustained morphine treatment followed by naloxone (Zhang et al., 2009)

This conservative start reveals any unexpected sensitivities

[50] Additionally, vitamin B12 is crucial for neurological functioning and can impact cognitive function, especially in older adults with mild deficiencies

[6] Exceptions exist when elimination is extremely rapid: for very short-acting agents, the phase can meaningfully shorten effect duration even after a single dose (e.g., triazolam, midazolam)