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GLP-1 analogs were subcutaneously injected once daily for 21 days

Ghrelin Rebound GLP-1 suppresses ghrelin (the hunger hormone)

Its effects on blood sugar management include: Enhanced glucose-dependent insulin secretion Suppression of glucagon release Reduced hepatic glucose output Improved peripheral insulin sensitivity In most patients, semaglutide's glucose-lowering effects more than compensate for any minor glucose-raising effect from CJC-1295

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