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Notably, these extracts (especially leaf extracts) showed enhanced effects in strengthening intracellular antioxidant defences like catalase, superoxide dismutase, and glutathione to lower lipid peroxidation products and reduce prominent pro-inflammatory markers such as tumor necrosis factor-, interleukin (1L)-, IL-6, monocyte chemoattractant protein-1 and nitric oxide synthase

The MAP kinase pathway mediates transcytosis induced by TNF- in an in vitro bloodbrain barrier model

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