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Moreover, in models of ischemiareperfusion injury and in KEAP1-inactivated lung cancer, inhibition or genetic ablation of CoQ biosynthetic enzymes restored sensitivity to ferroptosis or radiotherapy 115,116 , underscoring the reliance of some cancer cells on an abundant CoQ pool for redox defense and survival

Two-phase culture in Diamond Blackfan anemia: localization of erythroid defect

PMID: 28366460

Unfortunately, existing treatments exhibit limited ability to halt the progression of kidney injury in CKD, emphasizing the urgent need to delve into the precise molecular mechanisms governing the occurrence and development of CKD while identifying novel therapeutic targets