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Relationship between trimethylamine N-oxide and the risk of hypertension in patients with cardiovascular disease: a meta-analysis and dose-response relationship analysis

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However, with aging, the efficacy of key UPRER regulators such as PERK, IRE1, ATF6, among others, diminishes, leading to challenges in ER stress mitigation and an increased susceptibility to pathological UPRER activation [326,327,328]

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Before we start looking ahead, we want to take stock of where 2024 left the AOM market

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