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[87] in patients with type 2 diabetes (T2DM) observed that semaglutide treatment resulted in a reduction in absolute fat-free mass, yet an increased proportion of fat-free mass relative to total body weight, further supporting its mechanism of preferential fat reduction

Given the drugs success in tumor penetration, the researchers investigated whether adding immune checkpoint inhibitors to treatment with the drug would be even more effective, taking the brakes off T cells in more than one way at the same time but there was no such improvement

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