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GO enrichment analysis was performed with ClusterProfiler in R 67,84,85 (version 4.2.2) and GSEAPY for curated gene sets 86 in the scRNA-seq data, which were visualized in UMAP

This means that despite consuming a balanced diet, affected dogs might still face a B12 deficiency

A second hypothesis is that this pesticide reduces the conductance of open channels by binding to a site within the channel pore, preventing Na + and Ca +2 ions from entering the nerve cell

Additionally, in the atherosclerotic mouse model induced by a WD, dysbiosis leads to a significant increase in inflammation-associated microbiota, such as Desulfovibrio , Tyzzerella , and Lachnospiraceae-ge