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16 of patients had metastatic neuroblastoma and other had solid tumors with B7H3 expression, including medulloblastoma, ependymoma, melanoma and rhabdomyosarcoma, choroid plexus carcinoma, atypical thabdoid teratoma, chordoma, pineoblastoma and retinoblastoma

PubMed Kleinert, M., Sachs, S., Habegger, K.M., Hofmann, S.M., & Mller, T.D

The study documented hair follicle-stimulating properties, with topical application resulting in increased follicle activity compared to controls (Uno & Kubo, 1992)

While topical products may be adequate for mild surface-level concerns, addressing established skin laxity with significant collagen and elastin loss typically requires the higher tissue concentrations achievable through injection