This review initially focuses on sulfur assimilation systems, the biosynthesis of established sulfur-containing metabolites (Cys, Met, GSH, and SAM) and highlights potential antifungal drug targets
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SLC7A11 disruption in PDAC cell lines strongly affects their amino acid and redox balance, and thus suppresses in vitro and delays in vivo their proliferative phenotype ( in vivo SLC7A11 knock out PDAC cells grew normally
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