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Engaging in regular physical activity not only helps to prevent constipation but also enhances circulation, which is crucial for preventing the swelling of veins that can lead to hemorrhoids

One side effect that stood out more at higher doses was dysesthesia or changes in skin sensation , which were reported much more often at 9 mg and 12 mg

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Individuals with a BMI of 27 kg/m or higher who also present with at least one weight-related comorbidity, such as hypertension or dyslipidemia