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Here, microdosing means one of two things: splitting the weekly dose into two or three injections per week, or starting below the 2mg Phase 2 dose as an off-label sensitivity protocol

Serum il-23 significantly decreased in obese patients with psoriatic arthritis six months after a structured weight loss intervention

1,2 For this reason, its important to further understand the mechanism of GLP-1 therapies, said Lorenzo Leggio, a neuroendocrinologist at the National Institute on Drug Abuse who mediated the GLP-1 press conference at the 2025 Society for Neuroscience meeting

3 For comparison, Mounjaro and Wegovy typically raise resting heart rate by 2 to 4 bpm