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Ozempic (semaglutide) and Mounjaro (tirzepatide) are FDA-approved primarily for the treatment of adults with type 2 diabetes mellitus to improve blood sugar control and reduce the risk of major cardiovascular events in adults with type 2 diabetes and established cardiovascular disease

Ozempic works through several complementary mechanisms: it stimulates insulin secretion from the pancreas when blood glucose levels are elevated, suppresses the release of glucagon (a hormone that raises blood sugar), slows gastric emptying to reduce post-meal glucose spikes, and acts on appetite centres in the brain to promote satiety

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