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For samples derived from media containing 13 C glucose or 13 C glutamine, methoximation was followed by silylation by adding 80 l of MTBSTFA (with 1% TBDMS, Thermo) and incubation for 60 min at 70 C

OMIM #236270), or impaired supply of the cofactor methylcobalamin (cblC

We also maintain our interest in whether equivalent pre- and post-procedure urine cultures from patients in both study groups would have yielded different results, which the applicant agreed would have produced different evidence related to UTI incidence