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Statins show a protective role against HCC as they decrease hepatic expression of angiogenic factors like VEGF receptor, epidermal growth factor receptor (EGFR), and platelet-derived growth factor (PDGF) (Dulak and Jzkowicz, 2005

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However, we did find a small increased risk of NAION with exenatide use when using the specific NAION definition. Future research should incorporate ocular risk factors or examine dose-dependent effects to continue to investigate a potential causal relationship between semaglutide and NAION, they added

Gate downsampling was set to alive cells, sample size to 5000 events (all together 120000 events from 24 files being merged for t-SNE)