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Substituting GIPRs C-terminal tail with that of GLP-1R significantly increased both the rate and extent of agonist-mediated endocytosis, suggesting a role for GIPRs C-terminal region in either its slower internalization or rapid recycling back to the plasma membrane

Furthermore, the ability of MenSCs to promote germ cell differentiation has increased their therapeutic utility in treating ovarian disorders

Furthermore, immune-related studies have confirmed that amino acid metabolism regulates the function of effector T cells and regulatory T cells, affecting the function of immune cells