During the regulatory-required cardiovascular outcome safety trials in individuals with diabetes and at high risk for cardiovascular events, SGLT2is demonstrated powerful cardiovascular and kidney protection beyond what could be expected from improved glucose management alone [52,53]
What his study highlighted that if you put two different drugs together, the antimalarials tafenoquine and atovaquone, to treat Babesiosis in mice, they have the potential for not only a complete cure, but they show immune protection against reinfection of the Babesia parasite
Unlike the reversible albumin binding used by GLP-1 agonists, the DAC forms an irreversible bond with serum albumin, creating a circulating depot that extends the half-life of a GHRH analog from minutes to days
Promising avenues include EPA in conjunction with statins to target triglyceride-driven risk, CoQ10 supplementation to enhance myocardial energetics in heart failure, and magnesium repletion to reduce arrhythmogenic potential in at-risk populations ( Despite generally favorable tolerability profiles, supplementation is not devoid of risk
