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244 In addition, HDAC1 enhances basal autophagy by deacetylating ATG16L1, aiding in autophagosome elongation and supporting nutrient-deprived cell proliferation

However, weight loss induced by GLP-1RAs encompasses both fat and lean tissue compartments and could be associated to nutritional deficiencies, raising important questions regarding their impact on skeletal muscle, particularly in individuals at increased risk of sarcopenia [11]

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For example, due to our relatively small sample size we did not separate and analyze the volumes of strokes occurring in a particular vascular distribution