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These authors also found that the lactoferrin treatment lowered the serum concentration of IL6 from 32 to 12 pg/ml and therefore think that this mitigated inhibition of ferroportin 1 on macrophages and thereby enhanced iron export to blood for efficient erythropoiesis (Paesano et al., 2010)

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A healthy microbiota can ferment fiber to produce short-chain fatty acids (SCFAs), such as butyrate, which is not only an energy source for colonocytes but also has important immunomodulatory functions like regulating Treg cell differentiation and suppressing inflammation (66)

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