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Notably, limited data were available for people with BMI 40 kg m 2 , the elderly, adolescents and people with overweight (BMI 25 kg m 2 and 25 kg m 2 ), with a treatment duration of at least 48 weeks, which compared OMMs with the specific indication of obesity treatment with either placebo or other OMM

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For patients requiring substantial LDL-C lowering to reach guideline-recommended targets, statins or combination lipid therapy remain essential first-line treatments