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Description

The build-up of ROS induces ER stress, causing the release of damage-associated molecular patterns (DAMPs) like calreticulin, ATP and high mobility group box 1 [261, 262]

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Vial duration A 10 mg vial lasts ~5 weeks at 2 mg/week, ~2 weeks at 5 mg/week, and ~1 week at the upper 812 mg titration window

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