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Pre-clinical data suggests upregulation of nerve growth factor and vascular endothelial growth factor in injury models [9]

Paeonol also inhibited melanin transfer and PAR-2 activating peptide SLIGRL-induced melanin transfer during co-culture of melanocytes and keratinocytes ( 2.4 Others 2.4.1 Capsaicine Capsaicin, a unique alkaloid primarily found in Capsicum fruits (151), has been extensively investigated for its antioxidant, anti-inflammatory, analgesic, and anticancer properties (152155)

The core AEDG amino acid sequence, which is responsible for the compounds documented research activity, remains unchanged