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IECs counteract TNF by the production of various factors including the ubiquitin-editing enzyme, A20, required for the termination of certain immune signalling pathways activated in response to surface detection of TNF or PAMPs (Brenchley and Douek 2012)

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Protein Engineered Variants of Hepatocyte Growth Factor/scatter Factor Promote Proliferation of Primary Human Hepatocytes and in Rodent Liver