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George Frey/Bloomberg via Getty Images Its hard to turn on the TV, read the news or make it through a conversation without hearing about Ozempic and other drugs like it that belong to a class of medications known as glucagon-like peptide-1 receptor agonists, or GLP-1s

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Despite lower efficacy and tolerability shown by nasally administered PYY agonists in early studies, long-acting subcutaneous PYY receptor agonists such as PYY 1875 are undergoing early-phase clinical trials to evaluate their safety and effectiveness as monotherapy or in combination with GLP-1 receptor agonists for the treatment of obesity