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A safety review in the Journal of Obesity & Food Metabolism describes six randomized, double-blind, placebo-controlled trials evaluating AOD-9604, including oral dosing studies and longer phase II programs

Ezetimibe and bempedoic acid may be alternatives if statins are insufficient or not well-tolerated

All FDA-approved AMPs were discovered in Gram-positive soil bacteria, and 98% of known AMPs also come from natural sources (skin secretions of frogs and toxins from different species)

Few articles have additionally recommended the consideration of rapid sequence induction, stating that there should be a low threshold for this method of securing the airway, especially in the setting of uncertainty regarding gastric contents (Joshi 2024