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Semaglutide injection and CV impact was evaluated using the SUSTAIN-6 trial (designed as a non-inferiority trials), which primarily showed a reduction in the rate of non-fatal stroke events (RR 0.61

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Its ability to activate GLP-1, glucagon, and GIP receptor pathways simultaneously has made retatrutide an important compound in modern metabolic research involving glycemic control, energy expenditure, and obesity-related signaling pathways