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Nat Rev Endocrinol 11 , 213227 (2015)

Conclusion To sum up, the findings of the present study may provide insight into the mechanism underlying Sirt1-regulated activation of microglia and neurological inflammation in the acute phase of stroke (Fig

it is known that obesity is accompanied by macrophage adipose tissue infiltration and macrophages secrete abundant inflammatory cytokines, which affect the metabolism of adipocytes