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34 Consequently, turnover of 5,10-methyleneTHF via the TYMS enzyme is proposed to be greater in 3R3R individuals, with a decrease in this vitamer and an increase in homocysteine levels previously observed in such individuals

May 2012;18(5):428-31

Peak hormone levels typically occur 3060 minutes after injection, making sermorelin most effective when dosed before sleep or in early morning when natural GH secretion is highest