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8 GLP-1R is expressed in model organisms and humans and is highly conserved and widely distributed in the body, 9,10 such as the pancreatic islets, central nervous system, stomach, heart, lung, liver and kidney

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Patient reports also highlight that semaglutide's appetite-suppressing effects reduce the mental burden of constant food noisea benefit many fibromyalgia patients value given the fatigue and cognitive challenges (often called 'fibro fog') that accompany the condition