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Healthcare providers may consider: Bacterial culture if infection is suspected Temporary discontinuation of semaglutide to assess symptom resolution Referral to allergy/immunology for suspected hypersensitivity reactions For type 2 diabetes patients only, alternative GLP-1 receptor agonist formulations (such as oral semaglutide/Rybelsus) if injection site reactions are recurrent and problematic Patients with confirmed hypersensitivity to semaglutide should not continue the medication

No statistical methods were used to predetermine sample sizes but our sample sizes are similar to those reported in our previous publications 8,57

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Due to the sensitive nature of laboratory reagents, UPLYFT does not accept returns on opened or reconstituted vials