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BC has recently captured considerable attention from the agriculture and environmental sustainability sectors due to its versatile applications in energy storage, ecological restoration, environmental damage reduction, and remediation of contaminated areas (Rajput et al

It carries a very high purity degree of collagen protein, leading to its high bioavailability and bioactivity

[DOI] [PMC free article] [PubMed] [Google Scholar] 105.Gonzalez-Hurtado E, Lee J, Choi J, Wolfgang MJ

In addition, Berberine reduces the release of inflammatory factors such as TNF- and IL-6 by inhibiting the CYP1B1 and NF-B pathways, upregulates miR-204 to target and regulate HIF1/NFATc2, inhibits the crosstalk between oxidative stress and inflammation, and suppresses abnormal cell apoptosis and fibrosis by regulating the Bax/Bcl-2 ratio and TGF-1 expression (Luo et al., 2021