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Drug interactions of exenatide were described in eight manuscripts [13, 20,21,22,23, 25, 33, 34], liraglutide in five [17, 19, 24, 26, 34], semaglutide in three [16, 18, 27], and lixisenatide, dulaglutide and albiglutide in two each [14, 15, 29,30,31,32] and synthetic GLP1 in one manuscript [28]
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According to research, the two notable modifications include the substitution of methionine and L-phenylalanine at the fourth and seventh positions with norleucine and D-phenylalanine, respectively
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