Historical Background and Scientific Context Scientific interest in metabolic regulatory enzymes expanded rapidly during the late twentieth century as molecular biology techniques improved
Keywords: primary senile degenerative dementia, alzheimers dementia, amyloid-, white matter, synaptic plasticity, methylene blue, hippocampal fibres, hippocampal ca1, axonal degeneration, alzheimer disease Introduction and background Alzheimer's disease (AD), the prevailing neurodegenerative disorder, is characterized by a progressive decline in cognitive abilities, ultimately resulting in profound dementia [1]
10.1007/s12035-014-9012-2 179 LeeS.-H.ChoiS.-M.YangE
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